The Microbiologist’s Guide to Safe Leftovers (2024)

Abundance is the point of Thanksgiving. It’s a holiday created to celebrate the harvest and be grateful for the richness in our lives.With abundance comes leftovers, if only to give the cooks a break for a day. And with leftovers comes the risk of food poisoning.

Leftovers are a dynamic environment where microorganisms, primarily bacteria, play a significant role,” says microbiologist Anne Moscona, MD. “All food can become a breeding ground for bacteria when it's left out at room temperature for too long. Eating food contaminated with bacteria can make you sick.”

We spoke with Moscona to find out more about microorganisms in leftovers and how to prevent getting sick.

How Bacteria Affects Food

Bacteria are microorganisms that are a natural part of the environment. They are everywhere. Cooking typically kills most bacteria, making the food safe for consumption. But, cooking does not eliminate all bacteria. And even after food is cooked to a safe internal temperature, bacteria can be reintroduced and reproduce.

Bacteria can be beneficial or harmful. The type of bacteria and conditions in which they grow makes all the difference.

Good Bacteria vs. Bad Bacteria

Some bacteria play important roles in food production and preservation. In food preservation (canning, pickling, fermenting), certain bacteria are intentionally used to preserve and flavor the food (jam, yogurt, cheese, sauerkraut, kimchi). These preservation processes create an environment that is inhospitable to harmful bacteria while allowing beneficial bacteria to thrive.

However, some bacteria have the potential to cause foodborne illnesses when consumed. These harmful bacteria—pathogenic, like salmonella, escherichia coli (E. coli), listeria, and campylobacter—can multiply rapidly if food is mishandled or stored improperly.

Bacteria in food thrive and multiply under specific conditions. Their favorite condition is temperature range is between 40°F and 140°F (4°C to 60°C), known as “The Danger Zone.”

Proper cooking, refrigeration, and re-heating help control bacterial growth.

Is the Smell Test Enough?

Sensory evaluation—smell, appearance, and taste tests—are useful indicators of food freshness and safety. However, they do not provide a complete assessment of what is safe to eat. “Smelling OK” should not make you eat a leftover that has been left out too long. Use these basic guidelines instead:

  • If leftovers smell or look weird (unlike themselves, foul, discolored, or textured), discard them.
  • If you are unsure about the food’s safety, discard it.

There is wastefulness connected to this method, but your health and that of your family come first. You can also purchase and prepare less.

Sharpies and Labels Are Your Friends

Write or label dates on leftovers to help you keep track of time. Leftovers are safest when consumed within 3-4 days. The longer leftovers are stored, the higher the risk of bacterial growth.

If the food looks or smells off, it should be discarded, even if it falls within the recommended time limits.

How to Store Leftovers

This is a story about leftovers, but storing food means anything you do with it besides cooking and eating: sitting on a plate or platter or table.

Cooked food needs to be refrigerated within two hours of cooking, whether you’ve already finished the meal or are waiting for it to start. After two hours, bacteria can start multiplying rapidly. Refrigerate leftovers within 1 hour of preparation if the food is exposed to temperatures above 90°F, like a hot car or picnic.

Within two hours of cooking, store food:

  • In the refrigerator, at or below 40°F
  • In or on a hot surface, above 140°F
  • Storing food at these temperature ranges slows down bacterial growth.

Freezing leftovers

If you can’t eat leftovers within 3-4 days, discard or freeze them. Properly packaged leftovers (airtight) can be safely stored for an extended period and enjoyed later. Some food, like seafood, dairy products, and cooked rice, spoil easily and should be discarded or frozen if you can’t eat within 1-2 days.

How to reheat leftovers

Leftovers and pre-cooked food should be heated to at least 165°F to kill bacteria that may have grown during storage. That means heat thoroughly, all the way through.

To see more about this topic, check out the CDC’s guide to food safety.

The Microbiologist’s Guide to Safe Leftovers (2024)

FAQs

How long can you keep leftover food before discarding 12 hours, 24 hours, 48 hours, 72 hours? ›

Leftovers can be kept for 3 to 4 days in the refrigerator. After that, the risk of food poisoning goes up. If you don't think you'll be able to eat leftovers within four days, freeze them right away. Frozen leftovers will stay safe for a long time.

What bacteria grow on food left out? ›

Staphylococcus aureus:Staphylococcus aureus bacteria can grow in food that's left out for too long. These bacteria are found nearly everywhere, from our skin to countertops, so it's very easy for food to become contaminated. Staphylococcus don't form spores, but they do make toxins that cause belly pain and diarrhea.

Do good bacteria survive cooking? ›

Fermented foods like sourdough starter, unpasteurized tempeh, kombucha, sauerkraut, miso and kimchi are teeming with live good bacteria. But cooking kills them. However, not all is lost if you boil your miso soup, cook tempeh (which you should do) or, obviously, bake your sourdough bread.

How do bacteria grow on cooked food? ›

These dormant spores are commonly found in farmland soils, in dust, on animals and field-grown vegetables and grains. And the spores can survive boiling temperatures. After a food is cooked and its temperature drops below 130 degrees, these spores germinate and begin to grow, multiply and produce toxins.

Can I eat leftovers from 2 days ago? ›

Discard all perishable foods, such as meat, poultry, eggs, side dishes, or casseroles, left at room temperature longer than two hours; one hour in room temperatures above 90 °F. Once leftovers are stored safely, they will remain safe three to four days.

Are leftovers good after 7 days? ›

According to the FDA Food Code, all perishable foods that are opened or prepared should be thrown out after 7 days, maximum. No leftovers should survive in your fridge for longer than that. Some foods should be even be thrown away before the 7 day mark.

Can you eat cooked rice after 5 days? ›

According to FoodSafety.gov, leftover white or brown rice is safe to eat for four to six days after being cooked and up to six months in the freezer. But that's only the half of it to ensure you don't get sick from a common cause of food poisoning.

Can you eat a ready meal 4 days out of date? ›

food cannot be supplied or served after its use-by date. high-risk ready-to-eat food should be kept for a maximum of 3 days in total (the day it is cooked or opened plus 2 days) unless there is evidence that it is safe to keep it for longer.

Can you eat leftovers that sat out all night? ›

Bacteria can grow rapidly on food left out at room temperature for more than 2 hours. If food is left out in a room or outdoors where the temperature is 90 degrees F or hotter, food should be refrigerated or discarded within just 1 hour. Myth: When I microwave food, the microwaves kill the bacteria.

What bacteria cannot be killed by cooking? ›

Staphylococcus aureus

aureus is allowed to grow in foods, it can produce a toxin that causes illness. Although cooking destroys the bacteria, the toxin produced is heat stable and may not be destroyed.

What kills most bacteria while cooking? ›

Leftovers and pre-cooked food should be heated to at least 165°F to kill bacteria that may have grown during storage. That means heat thoroughly, all the way through.

Does boiling soup make it safe? ›

If you do decide that you want to leave soup out overnight, it's recommended that you boil the soup for 10 minutes to kill any active bacteria.

What is the 4 hour food rule? ›

The 2-hour/4-hour rule outlines the time potentially hazardous food can be safely held between 5°C and 60°C. The rule was developed based on scientific studies. between 2 and 4 hours, the food can still be used, but can't be put back in the fridge • 4 hours or longer, the food must be thrown out.

Why is bread not a high-risk food? ›

Low risk foods are foods that do not provide ideal conditions for bacteria to grow. They are typically foods that are high in acid or sugar, as well as salted foods, dry foods or canned and vacuum-packed foods. Some examples of low risk foods include: Dry goods - Crackers, biscuits, flour, plain breads and rolls.

What is the Danger Zone in the kitchen? ›

The "Danger Zone" (40 °F-140 °F)

This range of temperatures is often called the "Danger Zone." That's why the Meat and Poultry Hotline advises consumers to never leave food out of refrigeration over 2 hours. If the temperature is above 90 °F, food should not be left out more than 1 hour.

How many days can you keep most food before discarding it? ›

Leftovers can be kept in the refrigerator for 3 to 4 days or frozen for 3 to 4 months. Although safe indefinitely, frozen leftovers can lose moisture and flavor when stored for longer times in the freezer.

How long can you keep perishable foods at room temperature before throwing out? ›

TWO HOURS is the MAXIMUM time perishable foods should be at room temperature (ONE HOUR at temperatures 90 degrees F and higher). This INCLUDES the time they're on the table during your meal. Just ONE bacterium, doubling every 20 minutes, can grow to over 2,097,152 bacteria in 7 hours!

How much time do you have to reheat food before it must be discarded? ›

The State Sanitary Code now requires that the entire mass of all cooked and refrigerated potentially hazardous food which is to be reheated must be reheated to 165 degrees Fahrenheit or above within two hours, and held above 140 degrees Fahrenheit until served.

References

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